Serveur d'exploration COVID et hydrochloroquine

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

A Survey-based Estimate of COVID-19 Incidence and Outcomes among Patients with Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension and Impact on the Process of Care.

Identifieur interne : 001A04 ( Main/Exploration ); précédent : 001A03; suivant : 001A05

A Survey-based Estimate of COVID-19 Incidence and Outcomes among Patients with Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension and Impact on the Process of Care.

Auteurs : Joshua D. Lee ; Charles D. Burger [États-Unis] ; Genecelle B. Delossantos ; Daniel Grinnan [États-Unis] ; David D. Ralph ; Sam G. Rayner ; John J. Ryan [États-Unis] ; Zeenat Safdar [États-Unis] ; Corey E. Ventetuolo [États-Unis] ; Roham T. Zamanian [États-Unis] ; Peter J. Leary [États-Unis]

Source :

RBID : pubmed:32726561

Descripteurs français

English descriptors

Abstract

Rationale: Patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) typically undergo frequent clinical evaluation. The incidence and outcomes of coronavirus disease (COVID-19) and its impact on routine management for patients with pulmonary vascular disease is currently unknown.Objectives: To assess the cumulative incidence and outcomes of recognized COVID-19 for patients with PAH/CTEPH followed at accredited pulmonary hypertension centers, and to evaluate the pandemic's impact on clinic operations at these centers.Methods: A survey was e-mailed to program directors of centers accredited by the Pulmonary Hypertension Association. Descriptive analyses and linear regression were used to analyze results.Results: Seventy-seven center directors were successfully e-mailed a survey, and 58 responded (75%). The cumulative incidence of COVID-19 recognized in individuals with PAH/CTEPH was 2.9 cases per 1,000 patients, similar to the general U.S. population. In patients with PAH/CTEPH for whom COVID-19 was recognized, 30% were hospitalized and 12% died. These outcomes appear worse than the general population. A large impact on clinic operations was observed including fewer clinic visits and substantially increased use of telehealth. A majority of centers curtailed diagnostic testing and a minority limited new starts of medical therapy. Most centers did not use experimental therapies in patients with PAH/CTEPH diagnosed with COVID-19.Conclusions: The cumulative incidence of COVID-19 recognized in patients with PAH/CTEPH appears similar to the broader population, although outcomes may be worse. Although the total number of patients with PAH/CTEPH recognized to have COVID-19 was small, the impact of COVID-19 on broader clinic operations, testing, and treatment was substantial.

DOI: 10.1513/AnnalsATS.202005-521OC
PubMed: 32726561
PubMed Central: PMC7706604


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">A Survey-based Estimate of COVID-19 Incidence and Outcomes among Patients with Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension and Impact on the Process of Care.</title>
<author>
<name sortKey="Lee, Joshua D" sort="Lee, Joshua D" uniqKey="Lee J" first="Joshua D" last="Lee">Joshua D. Lee</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Burger, Charles D" sort="Burger, Charles D" uniqKey="Burger C" first="Charles D" last="Burger">Charles D. Burger</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Pulmonary Medicine, Mayo Clinic Florida, Jacksonville, Florida.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>Department of Pulmonary Medicine, Mayo Clinic Florida, Jacksonville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Delossantos, Genecelle B" sort="Delossantos, Genecelle B" uniqKey="Delossantos G" first="Genecelle B" last="Delossantos">Genecelle B. Delossantos</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Grinnan, Daniel" sort="Grinnan, Daniel" uniqKey="Grinnan D" first="Daniel" last="Grinnan">Daniel Grinnan</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Medicine, Virginia Commonwealth University, Richmond, Virginia.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Virginie</region>
</placeName>
<wicri:cityArea>Department of Medicine, Virginia Commonwealth University, Richmond</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Ralph, David D" sort="Ralph, David D" uniqKey="Ralph D" first="David D" last="Ralph">David D. Ralph</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Rayner, Sam G" sort="Rayner, Sam G" uniqKey="Rayner S" first="Sam G" last="Rayner">Sam G. Rayner</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Ryan, John J" sort="Ryan, John J" uniqKey="Ryan J" first="John J" last="Ryan">John J. Ryan</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Medicine, University of Utah, Salt Lake City, Utah.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Utah</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Utah, Salt Lake City</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Safdar, Zeenat" sort="Safdar, Zeenat" uniqKey="Safdar Z" first="Zeenat" last="Safdar">Zeenat Safdar</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Medicine, Baylor College of Medicine, Houston, Texas.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
<wicri:cityArea>Department of Medicine, Baylor College of Medicine, Houston</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Ventetuolo, Corey E" sort="Ventetuolo, Corey E" uniqKey="Ventetuolo C" first="Corey E" last="Ventetuolo">Corey E. Ventetuolo</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Medicine and Health Services, Policy and Practice, Brown University, Providence, Rhode Island; and.</nlm:affiliation>
<orgName type="university">Université Brown</orgName>
<country>États-Unis</country>
<placeName>
<settlement type="city">Providence (Rhode Island)</settlement>
<region type="state">Rhode Island</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Zamanian, Roham T" sort="Zamanian, Roham T" uniqKey="Zamanian R" first="Roham T" last="Zamanian">Roham T. Zamanian</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Medicine, Stanford University, Stanford, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName>
<region type="state">Californie</region>
<settlement type="city">Stanford (Californie)</settlement>
</placeName>
<wicri:cityArea>Department of Medicine, Stanford University, Stanford</wicri:cityArea>
<orgName type="university">Université Stanford</orgName>
</affiliation>
</author>
<author>
<name sortKey="Leary, Peter J" sort="Leary, Peter J" uniqKey="Leary P" first="Peter J" last="Leary">Peter J. Leary</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Epidemiology, University of Washington, Seattle, Washington.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<wicri:cityArea>Department of Epidemiology, University of Washington, Seattle</wicri:cityArea>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32726561</idno>
<idno type="pmid">32726561</idno>
<idno type="doi">10.1513/AnnalsATS.202005-521OC</idno>
<idno type="pmc">PMC7706604</idno>
<idno type="wicri:Area/Main/Corpus">001039</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001039</idno>
<idno type="wicri:Area/Main/Curation">001039</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001039</idno>
<idno type="wicri:Area/Main/Exploration">001039</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">A Survey-based Estimate of COVID-19 Incidence and Outcomes among Patients with Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension and Impact on the Process of Care.</title>
<author>
<name sortKey="Lee, Joshua D" sort="Lee, Joshua D" uniqKey="Lee J" first="Joshua D" last="Lee">Joshua D. Lee</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Burger, Charles D" sort="Burger, Charles D" uniqKey="Burger C" first="Charles D" last="Burger">Charles D. Burger</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Pulmonary Medicine, Mayo Clinic Florida, Jacksonville, Florida.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>Department of Pulmonary Medicine, Mayo Clinic Florida, Jacksonville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Delossantos, Genecelle B" sort="Delossantos, Genecelle B" uniqKey="Delossantos G" first="Genecelle B" last="Delossantos">Genecelle B. Delossantos</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Grinnan, Daniel" sort="Grinnan, Daniel" uniqKey="Grinnan D" first="Daniel" last="Grinnan">Daniel Grinnan</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Medicine, Virginia Commonwealth University, Richmond, Virginia.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Virginie</region>
</placeName>
<wicri:cityArea>Department of Medicine, Virginia Commonwealth University, Richmond</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Ralph, David D" sort="Ralph, David D" uniqKey="Ralph D" first="David D" last="Ralph">David D. Ralph</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Rayner, Sam G" sort="Rayner, Sam G" uniqKey="Rayner S" first="Sam G" last="Rayner">Sam G. Rayner</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Ryan, John J" sort="Ryan, John J" uniqKey="Ryan J" first="John J" last="Ryan">John J. Ryan</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Medicine, University of Utah, Salt Lake City, Utah.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Utah</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Utah, Salt Lake City</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Safdar, Zeenat" sort="Safdar, Zeenat" uniqKey="Safdar Z" first="Zeenat" last="Safdar">Zeenat Safdar</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Medicine, Baylor College of Medicine, Houston, Texas.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
<wicri:cityArea>Department of Medicine, Baylor College of Medicine, Houston</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Ventetuolo, Corey E" sort="Ventetuolo, Corey E" uniqKey="Ventetuolo C" first="Corey E" last="Ventetuolo">Corey E. Ventetuolo</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Medicine and Health Services, Policy and Practice, Brown University, Providence, Rhode Island; and.</nlm:affiliation>
<orgName type="university">Université Brown</orgName>
<country>États-Unis</country>
<placeName>
<settlement type="city">Providence (Rhode Island)</settlement>
<region type="state">Rhode Island</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Zamanian, Roham T" sort="Zamanian, Roham T" uniqKey="Zamanian R" first="Roham T" last="Zamanian">Roham T. Zamanian</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Medicine, Stanford University, Stanford, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName>
<region type="state">Californie</region>
<settlement type="city">Stanford (Californie)</settlement>
</placeName>
<wicri:cityArea>Department of Medicine, Stanford University, Stanford</wicri:cityArea>
<orgName type="university">Université Stanford</orgName>
</affiliation>
</author>
<author>
<name sortKey="Leary, Peter J" sort="Leary, Peter J" uniqKey="Leary P" first="Peter J" last="Leary">Peter J. Leary</name>
<affiliation>
<nlm:affiliation>Department of Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
<wicri:noCountry code="no comma">Department of Medicine and.</wicri:noCountry>
</affiliation>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Epidemiology, University of Washington, Seattle, Washington.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<wicri:cityArea>Department of Epidemiology, University of Washington, Seattle</wicri:cityArea>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Annals of the American Thoracic Society</title>
<idno type="eISSN">2325-6621</idno>
<imprint>
<date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Adenosine Monophosphate (analogs & derivatives)</term>
<term>Adenosine Monophosphate (therapeutic use)</term>
<term>Adrenal Cortex Hormones (therapeutic use)</term>
<term>Alanine (analogs & derivatives)</term>
<term>Alanine (therapeutic use)</term>
<term>Antibodies, Monoclonal, Humanized (therapeutic use)</term>
<term>Antiviral Agents (therapeutic use)</term>
<term>Azithromycin (therapeutic use)</term>
<term>COVID-19 (drug therapy)</term>
<term>COVID-19 (epidemiology)</term>
<term>COVID-19 (therapy)</term>
<term>Cardiac Catheterization (statistics & numerical data)</term>
<term>Chloroquine (therapeutic use)</term>
<term>Chronic Disease (MeSH)</term>
<term>Computed Tomography Angiography (statistics & numerical data)</term>
<term>Delivery of Health Care (MeSH)</term>
<term>Echocardiography (statistics & numerical data)</term>
<term>Hospital Mortality (MeSH)</term>
<term>Hospitalization (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Hydroxychloroquine (therapeutic use)</term>
<term>Hypertension, Pulmonary (diagnosis)</term>
<term>Hypertension, Pulmonary (epidemiology)</term>
<term>Hypertension, Pulmonary (etiology)</term>
<term>Hypertension, Pulmonary (therapy)</term>
<term>Immunization, Passive (MeSH)</term>
<term>Incidence (MeSH)</term>
<term>Intensive Care Units (MeSH)</term>
<term>Pulmonary Arterial Hypertension (diagnosis)</term>
<term>Pulmonary Arterial Hypertension (epidemiology)</term>
<term>Pulmonary Arterial Hypertension (therapy)</term>
<term>Pulmonary Embolism (complications)</term>
<term>Pulmonary Embolism (diagnosis)</term>
<term>Pulmonary Embolism (epidemiology)</term>
<term>Pulmonary Embolism (therapy)</term>
<term>Surveys and Questionnaires (MeSH)</term>
<term>Telemedicine (statistics & numerical data)</term>
<term>United States (epidemiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>AMP (analogues et dérivés)</term>
<term>AMP (usage thérapeutique)</term>
<term>Alanine (analogues et dérivés)</term>
<term>Alanine (usage thérapeutique)</term>
<term>Angiographie par tomodensitométrie (statistiques et données numériques)</term>
<term>Anticorps monoclonaux humanisés (usage thérapeutique)</term>
<term>Antiviraux (usage thérapeutique)</term>
<term>Azithromycine (usage thérapeutique)</term>
<term>Cathétérisme cardiaque (statistiques et données numériques)</term>
<term>Chloroquine (usage thérapeutique)</term>
<term>Embolie pulmonaire (complications)</term>
<term>Embolie pulmonaire (diagnostic)</term>
<term>Embolie pulmonaire (thérapie)</term>
<term>Embolie pulmonaire (épidémiologie)</term>
<term>Enquêtes et questionnaires (MeSH)</term>
<term>Hormones corticosurrénaliennes (usage thérapeutique)</term>
<term>Hospitalisation (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Hydroxychloroquine (usage thérapeutique)</term>
<term>Hypertension pulmonaire (diagnostic)</term>
<term>Hypertension pulmonaire (thérapie)</term>
<term>Hypertension pulmonaire (épidémiologie)</term>
<term>Hypertension pulmonaire (étiologie)</term>
<term>Immunisation passive (MeSH)</term>
<term>Incidence (MeSH)</term>
<term>Maladie chronique (MeSH)</term>
<term>Mortalité hospitalière (MeSH)</term>
<term>Prestations des soins de santé (MeSH)</term>
<term>Télémédecine (statistiques et données numériques)</term>
<term>Unités de soins intensifs (MeSH)</term>
<term>Échocardiographie (statistiques et données numériques)</term>
<term>États-Unis (épidémiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en">
<term>Adenosine Monophosphate</term>
<term>Alanine</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Adenosine Monophosphate</term>
<term>Adrenal Cortex Hormones</term>
<term>Alanine</term>
<term>Antibodies, Monoclonal, Humanized</term>
<term>Antiviral Agents</term>
<term>Azithromycin</term>
<term>Chloroquine</term>
<term>Hydroxychloroquine</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en">
<term>United States</term>
</keywords>
<keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr">
<term>AMP</term>
<term>Alanine</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en">
<term>Pulmonary Embolism</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Hypertension, Pulmonary</term>
<term>Pulmonary Arterial Hypertension</term>
<term>Pulmonary Embolism</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Embolie pulmonaire</term>
<term>Hypertension pulmonaire</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>COVID-19</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>COVID-19</term>
<term>Hypertension, Pulmonary</term>
<term>Pulmonary Arterial Hypertension</term>
<term>Pulmonary Embolism</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Hypertension, Pulmonary</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en">
<term>Cardiac Catheterization</term>
<term>Computed Tomography Angiography</term>
<term>Echocardiography</term>
<term>Telemedicine</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr">
<term>Angiographie par tomodensitométrie</term>
<term>Cathétérisme cardiaque</term>
<term>Télémédecine</term>
<term>Échocardiographie</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>COVID-19</term>
<term>Hypertension, Pulmonary</term>
<term>Pulmonary Arterial Hypertension</term>
<term>Pulmonary Embolism</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr">
<term>Embolie pulmonaire</term>
<term>Hypertension pulmonaire</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr">
<term>AMP</term>
<term>Alanine</term>
<term>Anticorps monoclonaux humanisés</term>
<term>Antiviraux</term>
<term>Azithromycine</term>
<term>Chloroquine</term>
<term>Embolie pulmonaire</term>
<term>Hormones corticosurrénaliennes</term>
<term>Hydroxychloroquine</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Embolie pulmonaire</term>
<term>Hypertension pulmonaire</term>
<term>États-Unis</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr">
<term>Hypertension pulmonaire</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Chronic Disease</term>
<term>Delivery of Health Care</term>
<term>Hospital Mortality</term>
<term>Hospitalization</term>
<term>Humans</term>
<term>Immunization, Passive</term>
<term>Incidence</term>
<term>Intensive Care Units</term>
<term>Surveys and Questionnaires</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Enquêtes et questionnaires</term>
<term>Hospitalisation</term>
<term>Humains</term>
<term>Immunisation passive</term>
<term>Incidence</term>
<term>Maladie chronique</term>
<term>Mortalité hospitalière</term>
<term>Prestations des soins de santé</term>
<term>Unités de soins intensifs</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr">
<term>États-Unis</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<b>Rationale:</b>
Patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) typically undergo frequent clinical evaluation. The incidence and outcomes of coronavirus disease (COVID-19) and its impact on routine management for patients with pulmonary vascular disease is currently unknown.
<b>Objectives:</b>
To assess the cumulative incidence and outcomes of
<i>recognized</i>
COVID-19 for patients with PAH/CTEPH followed at accredited pulmonary hypertension centers, and to evaluate the pandemic's impact on clinic operations at these centers.
<b>Methods:</b>
A survey was e-mailed to program directors of centers accredited by the Pulmonary Hypertension Association. Descriptive analyses and linear regression were used to analyze results.
<b>Results:</b>
Seventy-seven center directors were successfully e-mailed a survey, and 58 responded (75%). The cumulative incidence of COVID-19 recognized in individuals with PAH/CTEPH was 2.9 cases per 1,000 patients, similar to the general U.S. population. In patients with PAH/CTEPH for whom COVID-19 was recognized, 30% were hospitalized and 12% died. These outcomes appear worse than the general population. A large impact on clinic operations was observed including fewer clinic visits and substantially increased use of telehealth. A majority of centers curtailed diagnostic testing and a minority limited new starts of medical therapy. Most centers did not use experimental therapies in patients with PAH/CTEPH diagnosed with COVID-19.
<b>Conclusions:</b>
The cumulative incidence of COVID-19 recognized in patients with PAH/CTEPH appears similar to the broader population, although outcomes may be worse. Although the total number of patients with PAH/CTEPH recognized to have COVID-19 was small, the impact of COVID-19 on broader clinic operations, testing, and treatment was substantial.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">32726561</PMID>
<DateCompleted>
<Year>2020</Year>
<Month>12</Month>
<Day>10</Day>
</DateCompleted>
<DateRevised>
<Year>2021</Year>
<Month>03</Month>
<Day>05</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Electronic">2325-6621</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>17</Volume>
<Issue>12</Issue>
<PubDate>
<Year>2020</Year>
<Month>12</Month>
</PubDate>
</JournalIssue>
<Title>Annals of the American Thoracic Society</Title>
<ISOAbbreviation>Ann Am Thorac Soc</ISOAbbreviation>
</Journal>
<ArticleTitle>A Survey-based Estimate of COVID-19 Incidence and Outcomes among Patients with Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension and Impact on the Process of Care.</ArticleTitle>
<Pagination>
<MedlinePgn>1576-1582</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1513/AnnalsATS.202005-521OC</ELocationID>
<Abstract>
<AbstractText>
<b>Rationale:</b>
Patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) typically undergo frequent clinical evaluation. The incidence and outcomes of coronavirus disease (COVID-19) and its impact on routine management for patients with pulmonary vascular disease is currently unknown.
<b>Objectives:</b>
To assess the cumulative incidence and outcomes of
<i>recognized</i>
COVID-19 for patients with PAH/CTEPH followed at accredited pulmonary hypertension centers, and to evaluate the pandemic's impact on clinic operations at these centers.
<b>Methods:</b>
A survey was e-mailed to program directors of centers accredited by the Pulmonary Hypertension Association. Descriptive analyses and linear regression were used to analyze results.
<b>Results:</b>
Seventy-seven center directors were successfully e-mailed a survey, and 58 responded (75%). The cumulative incidence of COVID-19 recognized in individuals with PAH/CTEPH was 2.9 cases per 1,000 patients, similar to the general U.S. population. In patients with PAH/CTEPH for whom COVID-19 was recognized, 30% were hospitalized and 12% died. These outcomes appear worse than the general population. A large impact on clinic operations was observed including fewer clinic visits and substantially increased use of telehealth. A majority of centers curtailed diagnostic testing and a minority limited new starts of medical therapy. Most centers did not use experimental therapies in patients with PAH/CTEPH diagnosed with COVID-19.
<b>Conclusions:</b>
The cumulative incidence of COVID-19 recognized in patients with PAH/CTEPH appears similar to the broader population, although outcomes may be worse. Although the total number of patients with PAH/CTEPH recognized to have COVID-19 was small, the impact of COVID-19 on broader clinic operations, testing, and treatment was substantial.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Lee</LastName>
<ForeName>Joshua D</ForeName>
<Initials>JD</Initials>
<Identifier Source="ORCID">0000-0001-7715-2107</Identifier>
<AffiliationInfo>
<Affiliation>Department of Medicine and.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Burger</LastName>
<ForeName>Charles D</ForeName>
<Initials>CD</Initials>
<AffiliationInfo>
<Affiliation>Department of Pulmonary Medicine, Mayo Clinic Florida, Jacksonville, Florida.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Delossantos</LastName>
<ForeName>Genecelle B</ForeName>
<Initials>GB</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine and.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Grinnan</LastName>
<ForeName>Daniel</ForeName>
<Initials>D</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine, Virginia Commonwealth University, Richmond, Virginia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ralph</LastName>
<ForeName>David D</ForeName>
<Initials>DD</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine and.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Rayner</LastName>
<ForeName>Sam G</ForeName>
<Initials>SG</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine and.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ryan</LastName>
<ForeName>John J</ForeName>
<Initials>JJ</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine, University of Utah, Salt Lake City, Utah.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Safdar</LastName>
<ForeName>Zeenat</ForeName>
<Initials>Z</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine, Baylor College of Medicine, Houston, Texas.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ventetuolo</LastName>
<ForeName>Corey E</ForeName>
<Initials>CE</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine and Health Services, Policy and Practice, Brown University, Providence, Rhode Island; and.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Zamanian</LastName>
<ForeName>Roham T</ForeName>
<Initials>RT</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine, Stanford University, Stanford, California.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Leary</LastName>
<ForeName>Peter J</ForeName>
<Initials>PJ</Initials>
<Identifier Source="ORCID">0000-0001-5716-248X</Identifier>
<AffiliationInfo>
<Affiliation>Department of Medicine and.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Epidemiology, University of Washington, Seattle, Washington.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo>
<Country>United States</Country>
<MedlineTA>Ann Am Thorac Soc</MedlineTA>
<NlmUniqueID>101600811</NlmUniqueID>
<ISSNLinking>2325-6621</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000305">Adrenal Cortex Hormones</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D061067">Antibodies, Monoclonal, Humanized</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>3QKI37EEHE</RegistryNumber>
<NameOfSubstance UI="C000606551">remdesivir</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>415SHH325A</RegistryNumber>
<NameOfSubstance UI="D000249">Adenosine Monophosphate</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>4QWG6N8QKH</RegistryNumber>
<NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>83905-01-5</RegistryNumber>
<NameOfSubstance UI="D017963">Azithromycin</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>886U3H6UFF</RegistryNumber>
<NameOfSubstance UI="D002738">Chloroquine</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>I031V2H011</RegistryNumber>
<NameOfSubstance UI="C502936">tocilizumab</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>OF5P57N2ZX</RegistryNumber>
<NameOfSubstance UI="D000409">Alanine</NameOfSubstance>
</Chemical>
</ChemicalList>
<SupplMeshList>
<SupplMeshName Type="Protocol" UI="C000705127">COVID-19 drug treatment</SupplMeshName>
<SupplMeshName Type="Protocol" UI="C000705128">COVID-19 serotherapy</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList>
<CommentsCorrections RefType="CommentIn">
<RefSource>Ann Am Thorac Soc. 2020 Dec;17(12):1528-1530</RefSource>
<PMID Version="1">33258672</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000249" MajorTopicYN="N">Adenosine Monophosphate</DescriptorName>
<QualifierName UI="Q000031" MajorTopicYN="N">analogs & derivatives</QualifierName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000305" MajorTopicYN="N">Adrenal Cortex Hormones</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000409" MajorTopicYN="N">Alanine</DescriptorName>
<QualifierName UI="Q000031" MajorTopicYN="N">analogs & derivatives</QualifierName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D061067" MajorTopicYN="N">Antibodies, Monoclonal, Humanized</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017963" MajorTopicYN="N">Azithromycin</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006328" MajorTopicYN="N">Cardiac Catheterization</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D002738" MajorTopicYN="N">Chloroquine</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D002908" MajorTopicYN="N">Chronic Disease</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000072226" MajorTopicYN="N">Computed Tomography Angiography</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D003695" MajorTopicYN="N">Delivery of Health Care</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D004452" MajorTopicYN="N">Echocardiography</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017052" MajorTopicYN="N">Hospital Mortality</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006976" MajorTopicYN="N">Hypertension, Pulmonary</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007116" MajorTopicYN="N">Immunization, Passive</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015994" MajorTopicYN="N">Incidence</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007362" MajorTopicYN="N">Intensive Care Units</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000081029" MajorTopicYN="N">Pulmonary Arterial Hypertension</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D011655" MajorTopicYN="N">Pulmonary Embolism</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017216" MajorTopicYN="N">Telemedicine</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D014481" MajorTopicYN="N" Type="Geographic">United States</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="Y">COVID-19</Keyword>
<Keyword MajorTopicYN="Y">clinic operations</Keyword>
<Keyword MajorTopicYN="Y">outcomes</Keyword>
<Keyword MajorTopicYN="Y">telehealth</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData>
<History>
<PubMedPubDate PubStatus="pubmed">
<Year>2020</Year>
<Month>7</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2020</Year>
<Month>12</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez">
<Year>2020</Year>
<Month>7</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList>
<ArticleId IdType="pubmed">32726561</ArticleId>
<ArticleId IdType="doi">10.1513/AnnalsATS.202005-521OC</ArticleId>
<ArticleId IdType="pmc">PMC7706604</ArticleId>
</ArticleIdList>
<ReferenceList>
<Reference>
<Citation>Ther Adv Chronic Dis. 2017 Feb;8(2-3):47-64</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">28348727</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Lancet Infect Dis. 2020 Jul;20(7):776-777</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32224313</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):458-464</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32298251</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>JAMA. 2020 May 26;323(20):2052-2059</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32320003</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Infect Control Hosp Epidemiol. 2016 Nov;37(11):1272-1277</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">27514583</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Epidemiology. 2020 Jul;31(4):567-569</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32324625</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Int J Infect Dis. 2020 May;94:91-95</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32173574</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Appl Health Econ Health Policy. 2011 Sep 1;9(5):293-303</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21875160</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>BMC Fam Pract. 2019 Jul 3;20(1):92</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">31269902</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Pulm Circ. 2020 Apr 29;10(2):2045894020920153</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32426111</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Appl Health Econ Health Policy. 2011 Nov 1;9(6):377-87</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21888449</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>JAMA. 2020 Apr 21;323(15):1499-1500</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32159735</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Lancet Infect Dis. 2020 Jul;20(7):773</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32171390</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Arch Acad Emerg Med. 2020 Mar 24;8(1):e35</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32232218</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Chest. 2011 Mar;139(3):497-504</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">20724737</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Am Coll Surg. 2020 Aug;231(2):216-222.e2</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32360960</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Pulm Circ. 2020 Apr 27;10(2):2045894020922799</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32426113</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Eur Respir J. 2015 Oct;46(4):903-75</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">26318161</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Contemp Clin Trials Commun. 2015 Dec 30;2:54-60</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">29736446</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Am Coll Cardiol. 2020 May 12;75(18):2372-2375</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32199938</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Heart Lung Transplant. 2020 Jul;39(7):729-730</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">32360293</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>N Engl J Med. 2009 Jul 9;361(2):112-5</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19474417</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Cardiol Clin. 2016 Aug;34(3):489-500</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">27443143</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations>
<list>
<country>
<li>États-Unis</li>
</country>
<region>
<li>Californie</li>
<li>Floride</li>
<li>Rhode Island</li>
<li>Texas</li>
<li>Utah</li>
<li>Virginie</li>
<li>Washington (État)</li>
</region>
<settlement>
<li>Providence (Rhode Island)</li>
<li>Seattle</li>
<li>Stanford (Californie)</li>
</settlement>
<orgName>
<li>Université Brown</li>
<li>Université Stanford</li>
<li>Université de Washington</li>
</orgName>
</list>
<tree>
<noCountry>
<name sortKey="Delossantos, Genecelle B" sort="Delossantos, Genecelle B" uniqKey="Delossantos G" first="Genecelle B" last="Delossantos">Genecelle B. Delossantos</name>
<name sortKey="Lee, Joshua D" sort="Lee, Joshua D" uniqKey="Lee J" first="Joshua D" last="Lee">Joshua D. Lee</name>
<name sortKey="Ralph, David D" sort="Ralph, David D" uniqKey="Ralph D" first="David D" last="Ralph">David D. Ralph</name>
<name sortKey="Rayner, Sam G" sort="Rayner, Sam G" uniqKey="Rayner S" first="Sam G" last="Rayner">Sam G. Rayner</name>
</noCountry>
<country name="États-Unis">
<region name="Floride">
<name sortKey="Burger, Charles D" sort="Burger, Charles D" uniqKey="Burger C" first="Charles D" last="Burger">Charles D. Burger</name>
</region>
<name sortKey="Grinnan, Daniel" sort="Grinnan, Daniel" uniqKey="Grinnan D" first="Daniel" last="Grinnan">Daniel Grinnan</name>
<name sortKey="Leary, Peter J" sort="Leary, Peter J" uniqKey="Leary P" first="Peter J" last="Leary">Peter J. Leary</name>
<name sortKey="Ryan, John J" sort="Ryan, John J" uniqKey="Ryan J" first="John J" last="Ryan">John J. Ryan</name>
<name sortKey="Safdar, Zeenat" sort="Safdar, Zeenat" uniqKey="Safdar Z" first="Zeenat" last="Safdar">Zeenat Safdar</name>
<name sortKey="Ventetuolo, Corey E" sort="Ventetuolo, Corey E" uniqKey="Ventetuolo C" first="Corey E" last="Ventetuolo">Corey E. Ventetuolo</name>
<name sortKey="Zamanian, Roham T" sort="Zamanian, Roham T" uniqKey="Zamanian R" first="Roham T" last="Zamanian">Roham T. Zamanian</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidChloroV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001A04 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001A04 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    CovidChloroV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:32726561
   |texte=   A Survey-based Estimate of COVID-19 Incidence and Outcomes among Patients with Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension and Impact on the Process of Care.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:32726561" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a CovidChloroV1 

Wicri

This area was generated with Dilib version V0.6.38.
Data generation: Sat May 22 17:02:32 2021. Site generation: Sat May 22 17:06:52 2021